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INGREDIENTS:
Water (S), Butylene Glycol (S), C12-15 Alkyl Benzoate (M),
Phenoxyethanol (and) Methylparaben (and) Butylparaben (and) Propylparaben
(and) Ethylparaben (P), Sodium Hyaluronate (M), Natto Gum (AO),
Butylated Hydroxytolulene (AO), Retinaldehyde (A), PEG-40 Hydrogenated
Castor Oil (M), Sodium Bisulfite (AO).
Codebreaker: S = Solvent, M = Moisturiser, P = Preservative,
AO = Anti-oxidant, A = Vitamin A.
RETINALDEHYDE
Vitamin A has been used in dermatology for many years in prescription and over-the-counter
forms. It has the ability to repair signs of sun damage and premature ageing
such as wrinkles, pigmentation and rough, dry skin. Most forms of vitamin A are
irritating and can cause redness, peeling and sensitivity. Retinaldehyde is a
non-irritating Vitamin A metabolite which displays all of the benefits of vitamin
A therapy for the skin without causing undesirable side effects.
RECENT STUDIES
PHOTOAGEING
Clinical studies show significant reduction in the presentation of wrinkles and
roughness using 0.05%+ retinaldehyde. Other studies show the benefits of
retinaldehyde to be analogous to that of retinoic acid but without the irritant
effects. Clinical effects include epidermal thickening and repair of UVA-induced
collagen damage.
ACNE
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In
vitro modeling and in in vivo trials suggest retinaldehyde
shows significant (~99%) anti-bacterial activity against
P. acnes. |
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RAL
reduces comedones in the mouse model by more than
50% |
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33%
less erythema and no burning/pruritus compared
to ROL or RA. |
ROSACEA
Cultured human cell model studies indicate that retinaldehyde is effective in
decreasing vascular endothelial growth factor (VEGF), an angiogenic factor implicated
in angiogenesis-dependent skin disorders such as rosacea.
TOLERANCE
Retinaldehyde is shown to be very well tolerated at .05% concentrations
over extended (<3 years) time frames.
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retinaldehyde
serum
PATIENT
BENEFITS
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Provides
outstanding retinoid benefits with low irritancy profile. |
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Smooths
and clarifies skin tone and texture. |
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Increases
skin hydration. |
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Assists
repair following UV exposure and sun damage. |
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Illuminates
complexion and helps fade pigmentation. |
NEED
TO KNOW
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Use
RAL as a non-irritating alternative to RA, where patients
are intolerant of RA therapy or are non-compliant due
to side-effects |
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As
with all retinoids, avoid use during pregnancy. |
PRODUCT
USAGE
Use
nightly. Cleanse with Rationale Preparatory Cleanser.
Apply a few drops of Rationale Retinaldehyde Serum to face, neck, chest and backs
of hands. Follow with Rationale Skin Refining Serum and Rationale Moisture+ or
Enriched Hydration.
Rationale products are available from Mr Banwell's clinic please email for further details.
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